4M63

Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL

4M63 の概要

• エントリーDOI: 10.2210/pdb4m63/pdb
• 分子名称: T3SS2 effector VopL nucleation of actin polymerization, Actin-5C, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: actin nucleator, actin nucleation, hydrolase, wasp homology 2 domain, vopl c-terminal domain, cytoskeleton, atp-binding protein, actin-binding protein
• 由来する生物種: Vibrio parahaemolyticus; 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton: P10987
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 180700.27

構造登録者

Tomchick, D.R.,Zahm, J.A.,Rosen, M.K. (登録日: 2013-08-08, 公開日: 2013-10-23, 最終更新日: 2023-09-20)

• 主引用文献: Zahm, J.A.,Padrick, S.B.,Chen, Z.,Pak, C.W.,Yunus, A.A.,Henry, L.,Tomchick, D.R.,Chen, Z.,Rosen, M.K.; The Bacterial Effector VopL Organizes Actin into Filament-like Structures.; Cell(Cambridge,Mass.), 155:423-434, 2013; PubMed: 24120140; DOI: 10.1016/j.cell.2013.09.019

実験手法

X-RAY DIFFRACTION (2.748 Å)