4M1J

Crystal structure of Pseudomonas aeruginosa PvdQ in complex with a transition state analogue

Summary for 4M1J

Entry DOI	10.2210/pdb4m1j/pdb
Descriptor	Acyl-homoserine lactone acylase PvdQ subunit beta, Acyl-homoserine lactone acylase PvdQ subunit alpha, tridecylboronic acid, ... (5 entities in total)
Functional Keywords	transition state analogue, heterodimer, acylase, boronic acid, secreted, hydrolase
Biological source	Pseudomonas aeruginosa More
Cellular location	Periplasm : Q9I194 Q9I194
Total number of polymer chains	2
Total formula weight	80695.33
Authors	Wu, R.,Clevenger, K.,Er, J.,Fast, W.L.,Liu, D. (deposition date: 2013-08-02, release date: 2013-08-28, Last modification date: 2017-11-15)
Primary citation	Clevenger, K.D.,Wu, R.,Er, J.A.,Liu, D.,Fast, W. Rational Design of a Transition State Analogue with Picomolar Affinity for Pseudomonas aeruginosa PvdQ, a Siderophore Biosynthetic Enzyme. Acs Chem.Biol., 8:2192-2200, 2013 Cited by PubMed: 23883096 DOI: 10.1021/cb400345h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation