4M1D

Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN

Summary for 4M1D

• Entry DOI: 10.2210/pdb4m1d/pdb
• Descriptor: Fab mAb 447-52D Light Chain, Fab mAb 447-52D Heavy Chain, Cyclic V3 Arch Peptide, ... (5 entities in total)
• Functional Keywords: hiv, v3 loop, antibody-antigen interactions, envelope, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 99861.45

Authors

Killikelly, A.,Kong, X.P. (deposition date: 2013-08-02, release date: 2013-09-04, Last modification date: 2013-12-25)

• Primary citation: Killikelly, A.,Zhang, H.T.,Spurrier, B.,Williams, C.,Gorny, M.K.,Zolla-Pazner, S.,Kong, X.P.; Thermodynamic Signatures of the Antigen Binding Site of mAb 447-52D Targeting the Third Variable Region of HIV-1 gp120.; Biochemistry, 52:6249-6257, 2013; PubMed: 23944979; DOI: 10.1021/bi400645e

Experimental method

X-RAY DIFFRACTION (1.8 Å)