4LZJ

Crystal Structure of MurQ from H.influenzae with bound inhibitor

Summary for 4LZJ

• Entry DOI: 10.2210/pdb4lzj/pdb
• Related: 4M0D
• Descriptor: N-acetylmuramic acid 6-phosphate etherase, 2-(acetylamino)-3-O-[(1R)-1-carboxyethyl]-2-deoxy-6-O-phosphono-D-glucitol, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: alpha-beta-alpha sandwich, murq, yfeu, protein-ligand complex, nad(p)/fad-binding rossmann fold, d-muramitol 6-phosphate, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Haemophilus influenzae
• Total number of polymer chains: 4
• Total formula weight: 131199.41

Authors

Hazra, S.,Blanchard, J. (deposition date: 2013-07-31, release date: 2014-02-26, Last modification date: 2023-09-20)

• Primary citation: Hadi, T.,Hazra, S.,Tanner, M.E.,Blanchard, J.S.; Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor.; Biochemistry, 52:9358-9366, 2013; PubMed: 24251551; DOI: 10.1021/bi4010446

Experimental method

X-RAY DIFFRACTION (2.405 Å)