4LY8

dihydrodipicolinate synthase from C. jejuni with pyruvate bound to the active site

Summary for 4LY8

Entry DOI	10.2210/pdb4ly8/pdb
Related	4M19
Descriptor	4-hydroxy-tetrahydrodipicolinate synthase, 1,2-ETHANEDIOL, TRIETHYLENE GLYCOL, ... (7 entities in total)
Functional Keywords	schiff-base, aldolase, tim barrel, type 1 aldolase catalysing condensation of pyruvate and s-aspartate-b-semi-aldehyde, lyase
Biological source	Campylobacter jejuni subsp. jejuni
Cellular location	Cytoplasm : Q9PPB4
Total number of polymer chains	4
Total formula weight	138992.37
Authors	Conly, C.J.T. (deposition date: 2013-07-30, release date: 2015-01-14, Last modification date: 2024-04-03)
Primary citation	Conly, C.J.,Skovpen, Y.V.,Li, S.,Palmer, D.R.,Sanders, D.A. Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry, 53:7396-7406, 2014 Cited by PubMed: 25369463 DOI: 10.1021/bi5012157 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation