4LW7

Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP

Summary for 4LW7

• Entry DOI: 10.2210/pdb4lw7/pdb
• Related: 3LTP
• Descriptor: Orotidine 5'-phosphate decarboxylase, 6-HYDROXYURIDINE-5'-PHOSPHATE (3 entities in total)
• Functional Keywords: tim barrel fold, orotidine 5'-monophosphate decarboxylase, inhibitor bmp, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Methanothermobacter thermautotrophicus
• Total number of polymer chains: 2
• Total formula weight: 50347.62

Authors

Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C. (deposition date: 2013-07-26, release date: 2014-07-30, Last modification date: 2023-09-20)

• Primary citation: Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C.; Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP; To be Published,

Experimental method

X-RAY DIFFRACTION (1.423 Å)