4LU5

Structure of murine IgG2a A20G2-Fab in complex with vaccinia antigen A33R at the resolution of 2.9 Angstroms

Summary for 4LU5

• Entry DOI: 10.2210/pdb4lu5/pdb
• Related: 4LQF 4M1G
• Descriptor: A33R, Murine IgG2a A20G2 Heavy chain Fab domain, Murine IgG2a A20G2 Light chain Fab domain, ... (4 entities in total)
• Functional Keywords: igg domain, antibody-antigen complex, fv, ch1, igg2a, antigen-binding fragment (fab), a33r antigen, papain digest of the mab, eev membrane (outer membrane of vaccinia ev form), immune system
• Biological source: Vaccinia virus; More
• Total number of polymer chains: 6
• Total formula weight: 116702.02

Authors

Matho, M.H.,Schlossman, A.M.,Zajonc, D.M. (deposition date: 2013-07-24, release date: 2014-07-30, Last modification date: 2015-09-23)

• Primary citation: Matho, M.H.,Schlossman, A.,Meng, X.,Benhnia, M.R.,Kaever, T.,Buller, M.,Doronin, K.,Parker, S.,Peters, B.,Crotty, S.,Xiang, Y.,Zajonc, D.M.; Structural and Functional Characterization of Anti-A33 Antibodies Reveal a Potent Cross-Species Orthopoxviruses Neutralizer.; Plos Pathog., 11:e1005148-e1005148, 2015; PubMed: 26325270; DOI: 10.1371/journal.ppat.1005148

Experimental method

X-RAY DIFFRACTION (2.9 Å)