4LU3

The crystal structure of the human carbonic anhydrase XIV

Summary for 4LU3

• Entry DOI: 10.2210/pdb4lu3/pdb
• Descriptor: Carbonic anhydrase 14, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total)
• Functional Keywords: zinc binding, glycoprotein, membrane, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 33077.71

Authors

Alterio, V.,De Simone, G.,Monti, S.M. (deposition date: 2013-07-24, release date: 2014-01-01, Last modification date: 2023-09-20)

• Primary citation: Alterio, V.,Pan, P.,Parkkila, S.,Buonanno, M.,Supuran, C.T.,Monti, S.M.,De Simone, G.; The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitors.; Biopolymers, 101:769-778, 2014; PubMed: 24374484; DOI: 10.1002/bip.22456

Experimental method

X-RAY DIFFRACTION (2 Å)