4LS8
Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin
Summary for 4LS8
Entry DOI | 10.2210/pdb4ls8/pdb |
Related | 4ls5 4ls6 4ls7 |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 2, (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide, SODIUM ION, ... (6 entities in total) |
Functional Keywords | kasii, ketoacyl synthase, condensing enzyme, fatty acid elongation, cerulenin, drug target, transferase |
Biological source | Bacillus subtilis subsp. subtilis |
Total number of polymer chains | 2 |
Total formula weight | 91959.76 |
Authors | Trajtenberg, F.,Larrieux, N.,Buschiazzo, A. (deposition date: 2013-07-22, release date: 2014-04-02, Last modification date: 2024-10-09) |
Primary citation | Trajtenberg, F.,Altabe, S.,Larrieux, N.,Ficarra, F.,de Mendoza, D.,Buschiazzo, A.,Schujman, G.E. Structural insights into bacterial resistance to cerulenin. Febs J., 281:2324-2338, 2014 Cited by PubMed: 24641521DOI: 10.1111/febs.12785 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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