4LS8
Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | polymer | 426 | 45609.3 | 2 | UniProt (O34340) Pfam (PF00109) Pfam (PF02801) | Bacillus subtilis subsp. subtilis | 3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II |
| 2 | C, J (A, B) | (3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide | non-polymer | 225.3 | 2 | Chemie (1XG) | |||
| 3 | D, H, K (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | F, G, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 393 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 413 (UniProt: O34340)
| PDB | External Database | Details |
|---|---|---|
| Met -12 | - | initiating methionine |
| Arg -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Gln 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91218.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 741.2 | |
| All* | Total formula weight | 91959.8 |
