4LS8

Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a covalent complex with cerulenin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	3-oxoacyl-[acyl-carrier-protein] synthase 2	polymer	426	45609.3	2	UniProt (O34340) Pfam (PF00109) Pfam (PF02801) In PDB	Bacillus subtilis subsp. subtilis	3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II
2	A, B	(3R,7E,10E)-3-hydroxy-4-oxododeca-7,10-dienamide	non-polymer		225.3	2	Chemie (1XG)
3	A, B	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
4	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6		water	water		18.0	393	Chemie (HOH)

Sequence modifications

A, B: 1 - 413 (UniProt: O34340)

PDB	External Database	Details
Met -12	-	INITIATING METHIONINE
Arg -11	-	EXPRESSION TAG
Gly -10	-	EXPRESSION TAG
Ser -9	-	EXPRESSION TAG
His -8	-	EXPRESSION TAG
His -7	-	EXPRESSION TAG
His -6	-	EXPRESSION TAG
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
Gly -2	-	EXPRESSION TAG
Ile -1	-	EXPRESSION TAG
Gln 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91218.6
Non-Polymers*	Number of molecules	9
	Total formula weight	741.2
All*	Total formula weight	91959.8

*Water molecules are not included.