4LNP

The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin

Summary for 4LNP

• Entry DOI: 10.2210/pdb4lnp/pdb
• Related: 2MOX 4LN2
• Descriptor: Sorbin and SH3 domain-containing protein 1, Vinculin (3 entities in total)
• Functional Keywords: sh3 domain, cell migration, proline rich peptide, focal adhesion, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cell junction, adherens junction: Q9BX66; Cytoplasm, cytoskeleton : P18206
• Total number of polymer chains: 2
• Total formula weight: 8340.57

Authors

Zhao, D.,Li, F.,Wu, J.,Shi, Y.,Zhang, Z.,Gong, Q. (deposition date: 2013-07-11, release date: 2014-05-28, Last modification date: 2024-03-20)

• Primary citation: Zhao, D.,Wang, X.,Peng, J.,Wang, C.,Li, F.,Sun, Q.,Zhang, Y.,Zhang, J.,Cai, G.,Zuo, X.,Wu, J.,Shi, Y.,Zhang, Z.,Gong, Q.; Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin; J.Struct.Biol., 187:194-205, 2014; PubMed: 24878663; DOI: 10.1016/j.jsb.2014.05.009

Experimental method

X-RAY DIFFRACTION (1.41 Å)