4LN0

Crystal structure of the VGLL4-TEAD4 complex

4LN0 の概要

• エントリーDOI: 10.2210/pdb4ln0/pdb
• 分子名称: Transcriptional enhancer factor TEF-3, Transcription cofactor vestigial-like protein 4, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• 機能のキーワード: tea/atts domain family, vestigial/tondu family, transcription factor, transcription cofactor, development, transcription
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Nucleus: Q62296; Nucleus (By similarity): Q80V24
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 58678.17

構造登録者

Wang, H.,Shi, Z.,Zhou, Z. (登録日: 2013-07-11, 公開日: 2014-02-26, 最終更新日: 2023-11-08)

• 主引用文献: Jiao, S.,Wang, H.,Shi, Z.,Dong, A.,Zhang, W.,Song, X.,He, F.,Wang, Y.,Zhang, Z.,Wang, W.,Wang, X.,Guo, T.,Li, P.,Zhao, Y.,Ji, H.,Zhang, L.,Zhou, Z.; A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer.; Cancer Cell, 25:166-180, 2014; PubMed: 24525233; DOI: 10.1016/j.ccr.2014.01.010

実験手法

X-RAY DIFFRACTION (2.896 Å)