4LHV

Crystal structure of Rab8 in its inactive GDP-bound form

Summary for 4LHV

• Entry DOI: 10.2210/pdb4lhv/pdb
• Related: 4LHW 4LHX 4LHY 4LHZ 4LI0
• Descriptor: Ras-related protein Rab-8A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: small gtpase, protein transport
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P61006
• Total number of polymer chains: 5
• Total formula weight: 102177.13

Authors

Guo, Z.,Hou, X.M.,Goody, R.S.,Itzen, A. (deposition date: 2013-07-01, release date: 2013-10-09, Last modification date: 2023-09-20)

• Primary citation: Guo, Z.,Hou, X.,Goody, R.S.,Itzen, A.; Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB.; J.Biol.Chem., 288:32466-32474, 2013; PubMed: 24072714; DOI: 10.1074/jbc.M113.498329

Experimental method

X-RAY DIFFRACTION (1.95 Å)