4LHI

Crystal structure of human carbonic anhydrase isozyme II with 5-(phenylsulfonyl)thiophene-2-sulfonamide

Summary for 4LHI

• Entry DOI: 10.2210/pdb4lhi/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29814.12

Authors

Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2013-07-01, release date: 2014-07-02, Last modification date: 2023-11-08)

• Primary citation: Smirnov, A.,Manakova, E.,Grazulis, S.,Matulis, D.; Crystal structure of human carbonic anhydrase isozyme II with 5-(phenylsulfonyl)thiophene-2-sulfonamide; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)