4LE9

Crystal structure of a chimeric c-Src-SH3 domain

Summary for 4LE9

Entry DOI	10.2210/pdb4le9/pdb
Related	3FJ5 4JZ3 4JZ4
Descriptor	Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL (3 entities in total)
Functional Keywords	beta shandwich, sh3, kinase, proly proline rich motifs, phosphorylation, transferase
Biological source	Gallus gallus (bantam,chickens)
Cellular location	Cell membrane (By similarity): P00523
Total number of polymer chains	1
Total formula weight	8827.73
Authors	Camara-Artigas, A.,Martinez-Rodriguez, S.,Ortiz-Salmeron, E.,Martin-Garcia, J.M. (deposition date: 2013-06-25, release date: 2014-05-07, Last modification date: 2023-09-20)
Primary citation	Camara-Artigas, A.,Martinez-Rodriguez, S.,Ortiz-Salmeron, E.,Martin-Garcia, J.M. 3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops. J.Struct.Biol., 186:195-203, 2014 Cited by PubMed: 24556574 DOI: 10.1016/j.jsb.2014.02.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.344 Å)

Structure validation