4LDO

Structure of beta2 adrenoceptor bound to adrenaline and an engineered nanobody

Summary for 4LDO

Entry DOI	10.2210/pdb4ldo/pdb
Related	4LDE 4LDL
Descriptor	Lysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, ... (6 entities in total)
Functional Keywords	g protein coupled receptor, membrane protein-hydrolase complex, membrane protein/hydrolase
Biological source	Enterobacteria phage T4 More
Cellular location	Cell membrane ; Multi- pass membrane protein : P07550
Total number of polymer chains	2
Total formula weight	66950.03
Authors	Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. (deposition date: 2013-06-24, release date: 2013-09-25, Last modification date: 2023-09-20)
Primary citation	Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502:575-579, 2013 Cited by PubMed: 24056936 DOI: 10.1038/nature12572 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation