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4LDE

Structure of beta2 adrenoceptor bound to BI167107 and an engineered nanobody

Summary for 4LDE
Entry DOI10.2210/pdb4lde/pdb
Related4LDL 4LDO
DescriptorLysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, ... (6 entities in total)
Functional Keywordsg protein coupled receptor, membrane protein-hydrolase complex, membrane protein/hydrolase
Biological sourceEnterobacteria phage T4 (human)
More
Cellular locationCell membrane ; Multi- pass membrane protein : P07550
Total number of polymer chains2
Total formula weight67114.28
Authors
Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. (deposition date: 2013-06-24, release date: 2013-09-25, Last modification date: 2023-09-20)
Primary citationRing, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K.
Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody.
Nature, 502:575-579, 2013
Cited by
PubMed: 24056936
DOI: 10.1038/nature12572
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.79 Å)
Structure validation

218853

건을2024-04-24부터공개중

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