4LCW
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
Summary for 4LCW
Entry DOI | 10.2210/pdb4lcw/pdb |
Related | 4L4V |
Descriptor | Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, MAIT T cell receptor alpha chain, ... (7 entities in total) |
Functional Keywords | mhc class i-related protein, mait t cell receptor, vitamin b2 metabolites, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted: Q95460 Secreted: P61769 |
Total number of polymer chains | 8 |
Total formula weight | 187945.37 |
Authors | Patel, O.,Rossjohn, J. (deposition date: 2013-06-24, release date: 2013-10-02, Last modification date: 2023-09-20) |
Primary citation | Reantragoon, R.,Corbett, A.J.,Sakala, I.G.,Gherardin, N.A.,Furness, J.B.,Chen, Z.,Eckle, S.B.,Uldrich, A.P.,Birkinshaw, R.W.,Patel, O.,Kostenko, L.,Meehan, B.,Kedzierska, K.,Liu, L.,Fairlie, D.P.,Hansen, T.H.,Godfrey, D.I.,Rossjohn, J.,McCluskey, J.,Kjer-Nielsen, L. Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J.Exp.Med., 210:2305-2320, 2013 Cited by PubMed: 24101382DOI: 10.1084/jem.20130958 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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