4LCW
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31653.6 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class I-related gene protein, Class I histocompatibility antigen-like protein |
| 2 | B, F | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | D, G | MAIT T cell receptor alpha chain | polymer | 203 | 22650.1 | 2 | Pfam (PF07686) Pfam (PF09291) UniProt (by SIFTS) (Q6P4G7) In PDB | Homo sapiens (human) | |
| 4 | E, H | MAIT T cell receptor beta chain | polymer | 245 | 27546.6 | 2 | Pfam (PF07654) UniProt (by SIFTS) (P01850) In PDB | Homo sapiens (human) | |
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | A, C | 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol | non-polymer | 328.3 | 2 | Chemie (1VY) | |||
| 7 | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ala 43 | Lys 65 | engineered mutation |
| Ser 261 | Cys 283 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 187196.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 748.7 | |
| All* | Total formula weight | 187945.4 |
