4LC6

Crystal structure of the mutant H128Q of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP

Summary for 4LC6

• Entry DOI: 10.2210/pdb4lc6/pdb
• Related: 3LTP 4LC6
• Descriptor: Orotidine 5'-phosphate decarboxylase, 6-HYDROXYURIDINE-5'-PHOSPHATE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: ompdc barrel, orotidine 5'-monophosphate decarboxylase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Methanothermobacter thermautotrophicus
• Total number of polymer chains: 2
• Total formula weight: 50561.24

Authors

Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C. (deposition date: 2013-06-21, release date: 2013-07-03, Last modification date: 2023-09-20)

• Primary citation: Fedorov, A.A.,Fedorov, E.V.,Desai, B.,Gerlt, J.A.,Almo, S.C.; Crystal structure of the mutant H128Q of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP; To be Published,

Experimental method

X-RAY DIFFRACTION (1.32 Å)