4L4Y

Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition

4L4Y の概要

• エントリーDOI: 10.2210/pdb4l4y/pdb
• 関連するPDBエントリー: 4L4Z 4L50 4L51 4L5I 4L5J
• 分子名称: Transcriptional regulator LsrR (2 entities in total)
• 機能のキーワード: transcriptional regulator, phospho-ai-2 binding, dna binding, transcription regulator, removed helix-turn-helix domain, sorc/deor family
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm (Potential): P76141
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55848.26

構造登録者

Ryu, K.S.,Ha, J.H.,Eo, Y. (登録日: 2013-06-10, 公開日: 2013-11-06, 最終更新日: 2024-02-28)

• 主引用文献: Ha, J.H.,Eo, Y.,Grishaev, A.,Guo, M.,Smith, J.A.,Sintim, H.O.,Kim, E.H.,Cheong, H.K.,Bentley, W.E.,Ryu, K.S.; Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition.; J.Am.Chem.Soc., 135:15526-15535, 2013; PubMed: 24047255; DOI: 10.1021/ja407068v

実験手法

X-RAY DIFFRACTION (1.9 Å)