4L2Z

Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAE and PPi

4L2Z の概要

• エントリーDOI: 10.2210/pdb4l2z/pdb
• 関連するPDBエントリー: 4HPV 4K0B 4L7I
• 分子名称: S-adenosylmethionine synthase, MAGNESIUM ION, [(3S)-3-amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}ethyls ulfonium, ... (6 entities in total)
• 機能のキーワード: structural genomics, psi-biology, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, s-adenosylmethionine synthase, transferase
• 由来する生物種: Sulfolobus solfataricus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91392.36

構造登録者

Wang, F.,Hurley, K.A.,Helmich, K.E.,Singh, S.,Bingman, C.A.,Thorson, J.S.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2013-06-05, 公開日: 2013-06-19, 最終更新日: 2023-12-06)

• 主引用文献: Wang, F.,Singh, S.,Zhang, J.,Huber, T.D.,Helmich, K.E.,Sunkara, M.,Hurley, K.A.,Goff, R.D.,Bingman, C.A.,Morris, A.J.,Thorson, J.S.,Phillips, G.N.; Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.; Febs J., 281:4224-4239, 2014; PubMed: 24649856; DOI: 10.1111/febs.12784

実験手法

X-RAY DIFFRACTION (2.494 Å)