4L2O
Crystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazole
Summary for 4L2O
Entry DOI | 10.2210/pdb4l2o/pdb |
Related | 3SZA 3SZB 4L1O |
Descriptor | Aldehyde dehydrogenase, POTASSIUM ION, ACETATE ION, ... (6 entities in total) |
Functional Keywords | catalyzes benzaldehyde, rossmann fold, dehydrogenase, nadp+ binding, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P30838 |
Total number of polymer chains | 4 |
Total formula weight | 213307.77 |
Authors | Hurley, T.D.,Parajuli, B. (deposition date: 2013-06-04, release date: 2014-01-29, Last modification date: 2023-09-20) |
Primary citation | Parajuli, B.,Hurley, T.D. Crystal structure of human ALDH3A1 with its selective inhibitor 1-(4-fluorophenyl)sulfonyl-2-methylbenzimidazole J.Med.Chem., 2014 |
Experimental method | X-RAY DIFFRACTION (1.937 Å) |
Structure validation
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