4L29
Structure of wtMHC class I with NY-ESO1 double mutant
Summary for 4L29
Entry DOI | 10.2210/pdb4l29/pdb |
Related | 4L3C |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, NY-ESO1 DOUBLE MUTANT (1Y, 9V), ... (6 entities in total) |
Functional Keywords | mhc, beta-2 microglobulin, hla_a0201, ny-eso1, d76n variant, immunglobulin, beta sandwitch, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 42 |
Total formula weight | 632864.91 |
Authors | Halabelian, L.,Giorgetti, S.,Bellotti, V.,Bolognesi, M.,Ricagno, S. (deposition date: 2013-06-04, release date: 2013-12-25, Last modification date: 2014-02-26) |
Primary citation | Halabelian, L.,Ricagno, S.,Giorgetti, S.,Santambrogio, C.,Barbiroli, A.,Pellegrino, S.,Achour, A.,Grandori, R.,Marchese, L.,Raimondi, S.,Mangione, P.P.,Esposito, G.,Al-Shawi, R.,Simons, J.P.,Speck, I.,Stoppini, M.,Bolognesi, M.,Bellotti, V. Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin. J.Biol.Chem., 289:3318-3327, 2014 Cited by PubMed: 24338476DOI: 10.1074/jbc.M113.524157 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
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