4L0L
Crystal structure of P.aeruginosa PBP3 in complex with compound 4
Summary for 4L0L
Entry DOI | 10.2210/pdb4l0l/pdb |
Descriptor | Penicillin-binding protein 3, (6R,7S,10Z)-10-(2-amino-1,3-thiazol-4-yl)-1-(1,5-dihydroxy-4-oxo-1,4-dihydropyridin-2-yl)-7-formyl-13,13-dimethyl-3,9-dioxo-6-(sulfoamino)-12-oxa-2,4,8,11-tetraazatetradec-10-en-14-oic acid (3 entities in total) |
Functional Keywords | penicillin binding protein 3, penicillin binding protein-antibiotic complex, penicillin binding protein/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 1 |
Total formula weight | 58825.91 |
Authors | Han, S.,Marr, E.S. (deposition date: 2013-05-31, release date: 2013-08-21, Last modification date: 2014-01-22) |
Primary citation | Brown, M.F.,Mitton-Fry, M.J.,Arcari, J.T.,Barham, R.,Casavant, J.,Gerstenberger, B.S.,Han, S.,Hardink, J.R.,Harris, T.M.,Hoang, T.,Huband, M.D.,Lall, M.S.,Lemmon, M.M.,Li, C.,Lin, J.,McCurdy, S.P.,McElroy, E.,McPherson, C.,Marr, E.S.,Mueller, J.P.,Mullins, L.,Nikitenko, A.A.,Noe, M.C.,Penzien, J.,Plummer, M.S.,Schuff, B.P.,Shanmugasundaram, V.,Starr, J.T.,Sun, J.,Tomaras, A.,Young, J.A.,Zaniewski, R.P. Pyridone-conjugated monobactam antibiotics with gram-negative activity. J.Med.Chem., 56:5541-5552, 2013 Cited by PubMed: 23755848DOI: 10.1021/jm400560z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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