4KZV

Structure of the carbohydrate-recognition domain of the C-type lectin mincle bound to trehalose

Summary for 4KZV

• Entry DOI: 10.2210/pdb4kzv/pdb
• Related: 4KZW
• Related PRD ID: PRD_900006
• Descriptor: C-type lectin mincle, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: c-type lectin, carbohydrate-recognition domain, carbohydrate-binding protein
• Biological source: Bos taurus (bovine,cow,domestic cattle,domestic cow)
• Total number of polymer chains: 2
• Total formula weight: 32007.04

Authors

Feinberg, H.,Jegouzo, S.A.F.,Rowntree, T.J.W.,Guan, Y.,Brash, M.A.,Taylor, M.E.,Weis, W.I.,Drickamer, K. (deposition date: 2013-05-30, release date: 2013-08-28, Last modification date: 2020-07-29)

• Primary citation: Feinberg, H.,Jegouzo, S.A.,Rowntree, T.J.,Guan, Y.,Brash, M.A.,Taylor, M.E.,Weis, W.I.,Drickamer, K.; Mechanism for Recognition of an Unusual Mycobacterial Glycolipid by the Macrophage Receptor Mincle.; J.Biol.Chem., 288:28457-28465, 2013; PubMed: 23960080; DOI: 10.1074/jbc.M113.497149

Experimental method

X-RAY DIFFRACTION (1.4 Å)