4KYS
Clostridium botulinum thiaminase I in complex with thiamin
Summary for 4KYS
| Entry DOI | 10.2210/pdb4kys/pdb |
| Descriptor | Thiamine pyridinylase I, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CITRIC ACID, ... (5 entities in total) |
| Functional Keywords | periplasmic binding protein type 2 fold, thiaminase i, thiamin degradation, transferase |
| Biological source | Clostridium botulinum |
| Total number of polymer chains | 2 |
| Total formula weight | 99031.76 |
| Authors | Sikowitz, M.D.,Shome, B.,Zhang, Y.,Begley, T.P.,Ealick, S.E. (deposition date: 2013-05-29, release date: 2013-10-30, Last modification date: 2024-02-28) |
| Primary citation | Sikowitz, M.D.,Shome, B.,Zhang, Y.,Begley, T.P.,Ealick, S.E. Structure of a Clostridium botulinum C143S Thiaminase I/Thiamin Complex Reveals Active Site Architecture. Biochemistry, 52:7830-7839, 2013 Cited by PubMed: 24079939DOI: 10.1021/bi400841g PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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