4KV8
Crystal structure of HIV RT in complex with BILR0355BS
Summary for 4KV8
Entry DOI | 10.2210/pdb4kv8/pdb |
Related | 1RTH |
Related PRD ID | PRD_900003 |
Descriptor | HIV Reverse transcriptase P66, HIV Reverse transcriptase P51, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | nucleotidyltransferase, transferase |
Biological source | HIV-1 M:B_HXB2R (HIV-1) More |
Cellular location | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585 P04585 |
Total number of polymer chains | 2 |
Total formula weight | 117479.61 |
Authors | Coulombe, R. (deposition date: 2013-05-22, release date: 2013-07-31, Last modification date: 2024-02-28) |
Primary citation | Laplante, S.R.,Bilodeau, F.,Aubry, N.,Gillard, J.R.,O'Meara, J.,Coulombe, R. N- versus O-alkylation: Utilizing NMR methods to establish reliable primary structure determinations for drug discovery. Bioorg.Med.Chem.Lett., 23:4663-4668, 2013 Cited by PubMed: 23809849DOI: 10.1016/j.bmcl.2013.06.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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