4KV8
Crystal structure of HIV RT in complex with BILR0355BS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIV Reverse transcriptase P66 | polymer | 564 | 65047.6 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | HIV-1 M:B_HXB2R (HIV-1) | |
| 2 | B | HIV Reverse transcriptase P51 | polymer | 442 | 51543.2 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | HIV-1 M:B_HXB2R (HIV-1) | |
| 3 | C | beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900003) | sucrose | ||
| 4 | A | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
| 5 | A | 11-ethyl-5-methyl-8-[2-(1-oxidanylquinolin-4-yl)oxyethyl]dipyrido[3,2-[1,4]diazepin-6-one | non-polymer | 442.5 | 1 | Chemie (1WT) | |||
| 6 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A: 1 - 560 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Val 561 | - | expression tag |
| Pro 562 | - | expression tag |
| Arg 563 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116590.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 546.6 | |
| All* | Total formula weight | 117479.6 |
