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4KUY

Crystal structure of human carbonic anhydrase II in complex with the 5-(3-(o-tolylsulfonyl)ureido)pyridine-2-sulfonamide inhibitor

Summary for 4KUY
Entry DOI10.2210/pdb4kuy/pdb
Related4KUV 4KUW 4KV0
DescriptorCarbonic anhydrase 2, ZINC ION, BETA-MERCAPTOETHANOL, ... (6 entities in total)
Functional Keywordslyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00918
Total number of polymer chains1
Total formula weight29538.68
Authors
Ferraroni, M. (deposition date: 2013-05-22, release date: 2014-06-25, Last modification date: 2023-09-20)
Primary citationFerraroni, M.,Supuran, C.T.,Carta, F.,Bozdag, M.,Scozzafava, A.
New classes of carbonic anhydrase inhibitors
to be published,
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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