4KUV
Crystal structure of human carbonic anhydrase II in complex with the 5-(3-(4-chlorophenylsulfonyl)ureido)pyridine-2-sulfonamide inhibitor
Summary for 4KUV
Entry DOI | 10.2210/pdb4kuv/pdb |
Related | 4KUW 4KUY 4KV0 |
Descriptor | Carbonic anhydrase 2, ZINC ION, 5-({[(4-chlorophenyl)sulfonyl]carbamoyl}amino)pyridine-2-sulfonamide, ... (6 entities in total) |
Functional Keywords | lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29420.95 |
Authors | Ferraroni, M. (deposition date: 2013-05-22, release date: 2014-06-25, Last modification date: 2023-09-20) |
Primary citation | Ferraroni, M.,Supuran, C.T.,Carta, F.,Bozdag, M.,Scozzafava, A. New classes of carbonic anhydrase inhibitors to be published, |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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