4KUV

Crystal structure of human carbonic anhydrase II in complex with the 5-(3-(4-chlorophenylsulfonyl)ureido)pyridine-2-sulfonamide inhibitor

Summary for 4KUV

• Entry DOI: 10.2210/pdb4kuv/pdb
• Related: 4KUW 4KUY 4KV0
• Descriptor: Carbonic anhydrase 2, ZINC ION, 5-({[(4-chlorophenyl)sulfonyl]carbamoyl}amino)pyridine-2-sulfonamide, ... (6 entities in total)
• Functional Keywords: lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29420.95

Authors

Ferraroni, M. (deposition date: 2013-05-22, release date: 2014-06-25, Last modification date: 2023-09-20)

• Primary citation: Ferraroni, M.,Supuran, C.T.,Carta, F.,Bozdag, M.,Scozzafava, A.; New classes of carbonic anhydrase inhibitors; to be published,

Experimental method

X-RAY DIFFRACTION (1.35 Å)