4KTU
Bovine trypsin in complex with microviridin J at pH 6.5
Summary for 4KTU
Entry DOI | 10.2210/pdb4ktu/pdb |
Related | 3MYW 4KTS |
Related PRD ID | PRD_001086 |
Descriptor | Cationic trypsin, microviridin j, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | serine protease, hydrolase, natural product inhibitor, trypsin, protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Microcystis aeruginosa MRC More |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 2 |
Total formula weight | 25089.23 |
Authors | Quitterer, F.,Groll, M.,Hertweck, C.,Dittmann, E. (deposition date: 2013-05-21, release date: 2014-04-02, Last modification date: 2023-09-20) |
Primary citation | Weiz, A.R.,Ishida, K.,Quitterer, F.,Meyer, S.,Kehr, J.C.,Muller, K.M.,Groll, M.,Hertweck, C.,Dittmann, E. Harnessing the evolvability of tricyclic microviridins to dissect protease-inhibitor interactions. Angew.Chem.Int.Ed.Engl., 53:3735-3738, 2014 Cited by PubMed: 24591244DOI: 10.1002/anie.201309721 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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