4KQS

Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate

4KQS の概要

• エントリーDOI: 10.2210/pdb4kqs/pdb
• 関連するPDBエントリー: 4KFA 4KPD 4KPJ 4KQ5 4KQU
• 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: isoprene biosynthesis, lipid synthesis, steroid biosynthesis, transferase, dimethylallyl pyrophosphate, isoprenoid pathway, cholesterol synthesis, bisphosphonates
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P14324
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43655.01

構造登録者

Barnett, B.L.,Tsoumpra, M.K.,Muniz, J.R.C. (登録日: 2013-05-15, 公開日: 2014-04-30, 最終更新日: 2023-09-20)

• 主引用文献: Tsoumpra, M.K.,Muniz, J.R.C.,Barnett, B.L.,Pilka, E.,Kwaasi, A.,Kavanagh, K.L.,Evdokimov, A.G.,Walter, R.L.,Ebetino, F.H.,Oppermann, U.,Russell, R.G.G.,Dunford, J.E.; Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate; To be Published,

実験手法

X-RAY DIFFRACTION (1.97 Å)