4KQO

Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin

Summary for 4KQO

• Entry DOI: 10.2210/pdb4kqo/pdb
• Related: 4KQQ 4KQR
• Descriptor: Penicillin-binding protein 3, Piperacillin (Open Form), GLYCEROL, ... (6 entities in total)
• Functional Keywords: penicillin-binding proteins, piperacillin, cell wall biosynthesis, transpeptidase, out periplasmic membrane, biosynthetic protein-antibiotic complex, biosynthetic protein/antibiotic
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 123760.60

Authors

Nettleship, J.E.,Stuart, D.I.,Owens, R.J.,Ren, J. (deposition date: 2013-05-15, release date: 2013-11-06, Last modification date: 2023-09-20)

• Primary citation: van Berkel, S.S.,Nettleship, J.E.,Leung, I.K.,Brem, J.,Choi, H.,Stuart, D.I.,Claridge, T.D.,McDonough, M.A.,Owens, R.J.,Ren, J.,Schofield, C.J.; Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.; Acs Chem.Biol., 8:2112-2116, 2013; PubMed: 23899657; DOI: 10.1021/cb400200h

Experimental method

X-RAY DIFFRACTION (2.31 Å)