4KQO
Crystal structure of penicillin-binding protein 3 from pseudomonas aeruginosa in complex with piperacillin
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000917 | biological_process | division septum assembly |
A | 0004180 | molecular_function | carboxypeptidase activity |
A | 0005886 | cellular_component | plasma membrane |
A | 0006508 | biological_process | proteolysis |
A | 0008360 | biological_process | regulation of cell shape |
A | 0008658 | molecular_function | penicillin binding |
A | 0008955 | molecular_function | peptidoglycan glycosyltransferase activity |
A | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
A | 0009252 | biological_process | peptidoglycan biosynthetic process |
A | 0043093 | biological_process | FtsZ-dependent cytokinesis |
A | 0051301 | biological_process | cell division |
A | 0071555 | biological_process | cell wall organization |
B | 0000917 | biological_process | division septum assembly |
B | 0004180 | molecular_function | carboxypeptidase activity |
B | 0005886 | cellular_component | plasma membrane |
B | 0006508 | biological_process | proteolysis |
B | 0008360 | biological_process | regulation of cell shape |
B | 0008658 | molecular_function | penicillin binding |
B | 0008955 | molecular_function | peptidoglycan glycosyltransferase activity |
B | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
B | 0009252 | biological_process | peptidoglycan biosynthetic process |
B | 0043093 | biological_process | FtsZ-dependent cytokinesis |
B | 0051301 | biological_process | cell division |
B | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE JPP A 601 |
Chain | Residue |
A | SER294 |
A | ALA488 |
A | ARG489 |
A | TYR498 |
A | GLY534 |
A | HOH732 |
A | HOH829 |
A | HOH847 |
A | HOH849 |
A | TYR328 |
A | VAL333 |
A | SER349 |
A | ASN351 |
A | TYR409 |
A | SER485 |
A | GLY486 |
A | THR487 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 602 |
Chain | Residue |
A | GLY247 |
A | SER248 |
A | ARG284 |
A | PHE290 |
A | ASP525 |
A | HOH704 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 603 |
Chain | Residue |
A | SER435 |
A | MET436 |
A | THR437 |
site_id | AC4 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE JPP B 601 |
Chain | Residue |
B | SER294 |
B | TYR328 |
B | VAL333 |
B | SER349 |
B | ASN351 |
B | TYR409 |
B | LYS484 |
B | SER485 |
B | GLY486 |
B | THR487 |
B | ARG489 |
B | TYR498 |
B | HOH706 |
B | HOH762 |
B | HOH819 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL B 602 |
Chain | Residue |
B | GLY247 |
B | SER248 |
B | ARG284 |
B | PHE290 |
B | VAL523 |
B | ASP525 |
site_id | AC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE IMD B 603 |
Chain | Residue |
B | ARG551 |
B | ASN554 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 604 |
Chain | Residue |
B | LYS490 |
B | VAL491 |
B | ARG504 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL B 605 |
Chain | Residue |
B | ARG152 |
B | ARG273 |
B | ARG274 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_02080 |
Chain | Residue | Details |
A | SER294 | |
B | SER294 |