4KQK

Crystal structure of CobT S80Y/Q88M/L175M complexed with p-cresol

4KQK の概要

• エントリーDOI: 10.2210/pdb4kqk/pdb
• 関連するPDBエントリー: 1JHU 1JHV 4KQF 4KQG 4KQH 4KQI 4KQJ
• 分子名称: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, SULFATE ION, P-CRESOL, ... (6 entities in total)
• 機能のキーワード: transferase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74302.29

構造登録者

Chan, C.H.,Newmister, S.A.,Taylor, K.C.,Claas, K.R.,Rayment, I.,Escalante-Semerena, J.C. (登録日: 2013-05-15, 公開日: 2014-03-12, 最終更新日: 2024-11-20)

主引用文献

Chan, C.H.,Newmister, S.A.,Talyor, K.,Claas, K.R.,Rayment, I.,Escalante-Semerena, J.C.
Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica.
Biochim.Biophys.Acta, 1840:464-475, 2014

PubMed Abstract: Cobamide diversity arises from the nature of the nucleotide base. Nicotinate mononucleotide (NaMN):base phosphoribosyltransferases (CobT) synthesize α-linked riboside monophosphates from diverse nucleotide base substrates (e.g., benzimidazoles, purines, phenolics) that are incorporated into cobamides.

PubMed: 24121107
DOI: 10.1016/j.bbagen.2013.09.038

実験手法

X-RAY DIFFRACTION (1.47 Å)