Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0008939 | molecular_function | nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity |
A | 0009236 | biological_process | cobalamin biosynthetic process |
A | 0016757 | molecular_function | glycosyltransferase activity |
B | 0000166 | molecular_function | nucleotide binding |
B | 0008939 | molecular_function | nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity |
B | 0009236 | biological_process | cobalamin biosynthetic process |
B | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 401 |
Chain | Residue |
A | ARG38 |
A | ARG282 |
A | MET305 |
A | GLU306 |
A | HOH518 |
A | HOH531 |
site_id | AC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SO4 A 402 |
Chain | Residue |
A | GLY202 |
A | ALA203 |
A | HOH504 |
A | HOH535 |
A | HOH579 |
A | HOH607 |
A | HOH621 |
A | ALA178 |
A | ASN179 |
A | THR180 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE PCR A 403 |
Chain | Residue |
A | TYR80 |
A | HOH668 |
B | PRO32 |
B | LEU341 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 404 |
Chain | Residue |
A | GLN23 |
A | ASP27 |
A | GLU40 |
A | HOH533 |
A | HOH628 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 405 |
Chain | Residue |
A | ALA13 |
A | ASP15 |
A | PRO50 |
A | HOH582 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 406 |
Chain | Residue |
A | LEU323 |
A | PRO326 |
A | ILE327 |
B | LEU323 |
B | PRO326 |
site_id | AC7 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE SO4 B 701 |
Chain | Residue |
B | ALA178 |
B | ASN179 |
B | THR180 |
B | GLY202 |
B | ALA203 |
B | HOH824 |
B | HOH825 |
B | HOH920 |
B | HOH942 |
B | HOH944 |
B | HOH945 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 B 702 |
Chain | Residue |
B | ARG38 |
B | ARG282 |
B | PRO287 |
B | SER304 |
B | MET305 |
B | GLU306 |
B | HOH810 |
B | HOH906 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE PCR B 703 |
Chain | Residue |
A | LYS31 |
A | LEU341 |
B | HOH991 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | MET88 | |
B | MET88 | |
Chain | Residue | Details |
A | GLU174 | |
B | ARG314 | |
A | ALA203 | |
A | PHE265 | |
A | SER291 | |
A | ARG314 | |
B | GLU174 | |
B | ALA203 | |
B | PHE265 | |
B | SER291 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Important for substrate positioning, might be proton acceptor => ECO:0000269|PubMed:24121107 |
Chain | Residue | Details |
A | GLU174 | |
B | GLU174 | |
Chain | Residue | Details |
A | GLU317 | |
B | GLU317 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 2 |
Details | M-CSA 79 |
Chain | Residue | Details |
A | GLU174 | electrostatic stabiliser, unknown |
A | GLU317 | activator, hydrogen bond acceptor, proton acceptor, unknown |
site_id | MCSA2 |
Number of Residues | 2 |
Details | M-CSA 79 |
Chain | Residue | Details |
B | GLU174 | electrostatic stabiliser, unknown |
B | GLU317 | activator, hydrogen bond acceptor, proton acceptor, unknown |