4KNG

Crystal structure of human LGR5-RSPO1-RNF43

4KNG の概要

• エントリーDOI: 10.2210/pdb4kng/pdb
• 分子名称: Leucine-rich repeat-containing G-protein coupled receptor 5, R-spondin-1, E3 ubiquitin-protein ligase RNF43, ... (6 entities in total)
• 機能のキーワード: leucine-rich repeat, cysteine-rich domain, furin-repeat, protease-associated domain, ligand recognition, protein-protein interaction, n-linked glycosylation, membrane protein, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 178882.88

構造登録者

Chen, P.H.,He, X. (登録日: 2013-05-09, 公開日: 2013-06-19, 最終更新日: 2020-07-29)

• 主引用文献: Chen, P.H.,Chen, X.,Lin, Z.,Fang, D.,He, X.; The structural basis of R-spondin recognition by LGR5 and RNF43.; Genes Dev., 27:1345-1350, 2013; PubMed: 23756651; DOI: 10.1101/gad.219915.113

実験手法

X-RAY DIFFRACTION (2.5 Å)