4KN2
Human folate receptor beta (FOLR2) in complex with antifolate pemetrexed
Summary for 4KN2
Entry DOI | 10.2210/pdb4kn2/pdb |
Related | 4KM6 4KM7 4KMX 4KMY 4KMZ 4KN0 4KN1 |
Descriptor | Folate receptor beta, POTASSIUM ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | folate receptor beta, folr2, folate receptor, folic acid, folates, 5-methyltetrahydrofolate, antifolates, folate-conjugates, gpi-anchored protein on eukaryotic membrane, transport protein, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 74235.47 |
Authors | Wibowo, A.S.,Dann III, C.E. (deposition date: 2013-05-08, release date: 2013-08-07, Last modification date: 2023-09-20) |
Primary citation | Wibowo, A.S.,Singh, M.,Reeder, K.M.,Carter, J.J.,Kovach, A.R.,Meng, W.,Ratnam, M.,Zhang, F.,Dann, C.E. Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110:15180-15188, 2013 Cited by PubMed: 23934049DOI: 10.1073/pnas.1308827110 PDB entries with the same primary citation |
Experimental method |
Structure validation
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