4KEY
Structure of P450 BM3 A82F F87V in complex with omeprazole
Summary for 4KEY
Entry DOI | 10.2210/pdb4key/pdb |
Related | 4KEW 4KF0 4KF2 |
Descriptor | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, ... (4 entities in total) |
Functional Keywords | p450 heme domain, monooxygenase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Bacillus megaterium |
Cellular location | Cytoplasm (By similarity): P14779 |
Total number of polymer chains | 2 |
Total formula weight | 106286.84 |
Authors | Leys, D. (deposition date: 2013-04-26, release date: 2013-07-10, Last modification date: 2024-02-28) |
Primary citation | Butler, C.F.,Peet, C.,Mason, A.E.,Voice, M.W.,Leys, D.,Munro, A.W. Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288:25387-25399, 2013 Cited by PubMed: 23828198DOI: 10.1074/jbc.M113.479717 PDB entries with the same primary citation |
Experimental method |
Structure validation
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