4KEY
Structure of P450 BM3 A82F F87V in complex with omeprazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional P-450/NADPH-P450 reductase | polymer | 455 | 52197.5 | 2 | UniProt (P14779) Pfam (PF00067) | Bacillus megaterium | Cytochrome P450(BM-3), Cytochrome P450BM-3, Cytochrome P450 102, NADPH--cytochrome P450 reductase |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, F (A, B) | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole | non-polymer | 329.4 | 2 | Chemie (1C6) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 406 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 455 (UniProt: P14779)
| PDB | External Database | Details |
|---|---|---|
| Phe 82 | Ala 83 | engineered mutation |
| Val 87 | Phe 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104395.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1891.8 | |
| All* | Total formula weight | 106286.8 |
