4KEY

Structure of P450 BM3 A82F F87V in complex with omeprazole

Summary for 4KEY

Entry DOI	10.2210/pdb4key/pdb
Related	4KEW 4KF0 4KF2
Descriptor	Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, ... (4 entities in total)
Functional Keywords	p450 heme domain, monooxygenase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Bacillus megaterium
Cellular location	Cytoplasm (By similarity): P14779
Total number of polymer chains	2
Total formula weight	106286.84
Authors	Leys, D. (deposition date: 2013-04-26, release date: 2013-07-10, Last modification date: 2024-02-28)
Primary citation	Butler, C.F.,Peet, C.,Mason, A.E.,Voice, M.W.,Leys, D.,Munro, A.W. Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288:25387-25399, 2013 Cited by PubMed: 23828198 DOI: 10.1074/jbc.M113.479717 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation