4KBS

Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 phosphatidic acid (12:0 PA)

4KBS の概要

• エントリーDOI: 10.2210/pdb4kbs/pdb
• 関連するPDBエントリー: 4K80 4K84 4K85 4K8N 4KBR 4KF6
• 分子名称: Glycolipid transfer protein domain-containing protein 1, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: lipid transfer protein, gltp-fold, cptp, c1p, ceramide-1-phosphate, protein-lipid complex, eicosanoid, lipid transport
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50163.79

構造登録者

Simanshu, D.K.,Brown, R.E.,Patel, D.J. (登録日: 2013-04-23, 公開日: 2013-07-17, 最終更新日: 2024-04-03)

• 主引用文献: Simanshu, D.K.,Kamlekar, R.K.,Wijesinghe, D.S.,Zou, X.,Zhai, X.,Mishra, S.K.,Molotkovsky, J.G.,Malinina, L.,Hinchcliffe, E.H.,Chalfant, C.E.,Brown, R.E.,Patel, D.J.; Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.; Nature, 500:463-467, 2013; PubMed: 23863933; DOI: 10.1038/nature12332

実験手法

X-RAY DIFFRACTION (1.898 Å)