4K8Y

Atomic resolution crystal structures of Kallikrein-Related Peptidase 4 complexed with Sunflower Trypsin Inhibitor (SFTI-1)

4K8Y の概要

• エントリーDOI: 10.2210/pdb4k8y/pdb
• 関連するPDBエントリー: 1SFI 2bdg 2bdh 2bdi 4K1E 4KEL 4KGA
• 関連するBIRD辞書のPRD_ID: PRD_001097
• 分子名称: Kallikrein-4, Trypsin inhibitor 1 (3 entities in total)
• 機能のキーワード: bowman-birk inhibitor, protease, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: Q9Y5K2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 25461.84

構造登録者

Ilyichova, O.V.,Swedberg, J.E.,de Veer, S.J.,Sit, K.C.,Harris, J.M.,Buckle, A.M. (登録日: 2013-04-19, 公開日: 2014-04-23, 最終更新日: 2023-11-08)

• 主引用文献: Riley, B.T.,Ilyichova, O.,Costa, M.G.S.,Porebski, B.T.,de Veer, S.J.,Swedberg, J.E.,Kass, I.,Harris, J.M.,Hoke, D.E.,Buckle, A.M.; Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics; Sci Rep, 6:35385-35385, 2016; PubMed: 27767076; DOI: 10.1038/srep35385

実験手法

X-RAY DIFFRACTION (1 Å)