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4JZJ

Crystal Structure of Receptor-Fab Complex

Summary for 4JZJ
Entry DOI10.2210/pdb4jzj/pdb
DescriptorInterleukin-3 receptor subunit alpha, Fab Heavy Chain, Fab Light Chain, ... (9 entities in total)
Functional Keywordsreceptor-fab complex, cytokine receptor-immune system complex, cytokine receptor/immune system
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein: P26951
Total number of polymer chains6
Total formula weight165530.21
Authors
Broughton, S.E.,Parker, M.W. (deposition date: 2013-04-03, release date: 2014-04-09, Last modification date: 2020-07-29)
Primary citationBroughton, S.E.,Hercus, T.R.,Hardy, M.P.,McClure, B.J.,Nero, T.L.,Dottore, M.,Huynh, H.,Braley, H.,Barry, E.F.,Kan, W.L.,Dhagat, U.,Scotney, P.,Hartman, D.,Busfield, S.J.,Owczarek, C.M.,Nash, A.D.,Wilson, N.J.,Parker, M.W.,Lopez, A.F.
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody
Cell Rep, 8:410-419, 2014
Cited by
PubMed: 25043189
DOI: 10.1016/j.celrep.2014.06.038
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.801 Å)
Structure validation

217705

数据于2024-03-27公开中

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