4JZJ

Crystal Structure of Receptor-Fab Complex

4JZJ の概要

分子名称Interleukin-3 receptor subunit alpha, Fab Heavy Chain, Fab Light Chain, ... (10 entities in total)
機能のキーワードreceptor-fab complex, cytokine receptor-immune system complex, cytokine receptor/immune system
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Membrane; Single-pass type I membrane protein P26951
ポリマー鎖数6
分子量合計165746.39
構造登録者
Broughton, S.E.,Parker, M.W. (登録日: 2013-04-03, 公開日: 2014-04-09, 最終更新日: 2017-11-15)
主引用文献
Broughton, S.E.,Hercus, T.R.,Hardy, M.P.,McClure, B.J.,Nero, T.L.,Dottore, M.,Huynh, H.,Braley, H.,Barry, E.F.,Kan, W.L.,Dhagat, U.,Scotney, P.,Hartman, D.,Busfield, S.J.,Owczarek, C.M.,Nash, A.D.,Wilson, N.J.,Parker, M.W.,Lopez, A.F.
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody
Cell Rep, 8:410-419, 2014
PubMed: 25043189 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.celrep.2014.06.038
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.801 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24480.6%6.6%5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード