4JXT
CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD
Summary for 4JXT
Entry DOI | 10.2210/pdb4jxt/pdb |
Descriptor | Regulation of nuclear pre-mRNA domain-containing protein 1A, DNA-directed RNA polymerase II subunit RPB1, UNKNOWN ATOM OR ION, ... (4 entities in total) |
Functional Keywords | structural genomics consortium, structural genomics, sgc, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P24928 |
Total number of polymer chains | 2 |
Total formula weight | 18506.68 |
Authors | Ni, Z.,Xu, C.,Tempel, W.,El Bakkouri, M.,Loppnau, P.,Guo, X.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Greenblatt, J.F.,Structural Genomics Consortium (SGC) (deposition date: 2013-03-28, release date: 2013-11-13, Last modification date: 2023-09-20) |
Primary citation | Ni, Z.,Xu, C.,Guo, X.,Hunter, G.O.,Kuznetsova, O.V.,Tempel, W.,Marcon, E.,Zhong, G.,Guo, H.,Kuo, W.H.,Li, J.,Young, P.,Olsen, J.B.,Wan, C.,Loppnau, P.,El Bakkouri, M.,Senisterra, G.A.,He, H.,Huang, H.,Sidhu, S.S.,Emili, A.,Murphy, S.,Mosley, A.L.,Arrowsmith, C.H.,Min, J.,Greenblatt, J.F. RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21:686-695, 2014 Cited by PubMed: 24997600DOI: 10.1038/nsmb.2853 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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