4JTJ

Crystal structure of R117K mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

4JTJ の概要

• エントリーDOI: 10.2210/pdb4jtj/pdb
• 関連するPDBエントリー: 4JTE 4JTF 4JTG 4JTH 4JTI 4JTK 4JTL
• 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, transferase, lipopolysaccharide biosynthesis
• 由来する生物種: Neisseria meningitidis
• 細胞内の位置: Cytoplasm (By similarity): Q9JZ55
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 122094.60

構造登録者

Allison, T.M.,Cochrane, F.C.,Jameson, G.B.,Parker, E.J. (登録日: 2013-03-23, 公開日: 2013-06-26, 最終更新日: 2023-09-20)

• 主引用文献: Allison, T.M.,Cochrane, F.C.,Jameson, G.B.,Parker, E.J.; Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase.; Biochemistry, 52:4676-4686, 2013; PubMed: 23746359; DOI: 10.1021/bi400521f

実験手法

X-RAY DIFFRACTION (1.75 Å)