4JSV
mTOR kinase structure, mechanism and regulation.
Summary for 4JSV
Entry DOI | 10.2210/pdb4jsv/pdb |
Related | 4JSN 4JSP 4JSX 4JT5 |
Descriptor | Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | kinase, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P42345 Cytoplasm (By similarity): Q9BVC4 |
Total number of polymer chains | 4 |
Total formula weight | 342234.90 |
Authors | Pavletich, N.P.,Yang, H. (deposition date: 2013-03-22, release date: 2013-05-01, Last modification date: 2024-02-28) |
Primary citation | Yang, H.,Rudge, D.G.,Koos, J.D.,Vaidialingam, B.,Yang, H.J.,Pavletich, N.P. mTOR kinase structure, mechanism and regulation. Nature, 497:217-223, 2013 Cited by PubMed: 23636326DOI: 10.1038/nature12122 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
Download full validation report